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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
L1CAM
All Species:
23.33
Human Site:
Y418
Identified Species:
51.33
UniProt:
P32004
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32004
NP_000416.1
1257
140003
Y418
G
L
L
L
A
N
A
Y
I
Y
V
V
Q
L
P
Chimpanzee
Pan troglodytes
XP_001139376
1257
139970
Y418
G
L
L
L
A
N
A
Y
I
Y
V
V
Q
L
P
Rhesus Macaque
Macaca mulatta
XP_001087861
1257
139943
Y418
G
L
L
L
A
N
A
Y
I
Y
V
V
Q
L
P
Dog
Lupus familis
XP_549364
1256
140034
Y418
G
L
L
L
A
N
A
Y
I
Y
V
V
Q
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P11627
1260
140950
Y417
G
L
L
L
A
N
A
Y
I
Y
V
V
Q
L
P
Rat
Rattus norvegicus
Q05695
1259
140916
Y417
G
L
L
L
A
N
A
Y
I
Y
V
V
Q
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514797
764
86400
Chicken
Gallus gallus
Q03696
1266
136552
F411
G
P
L
L
A
N
A
F
L
H
V
V
E
L
P
Frog
Xenopus laevis
NP_001129635
1225
136897
T407
E
L
P
P
Q
I
L
T
K
N
D
E
Q
Y
S
Zebra Danio
Brachydanio rerio
Q90478
1197
132843
P391
R
T
F
G
S
P
L
P
K
I
H
W
E
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20241
1302
143599
K421
N
S
L
G
Y
V
Y
K
D
V
Y
L
N
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
91.9
N.A.
87.8
88.4
N.A.
36.3
47.3
48.1
38.1
N.A.
27.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.7
95.4
N.A.
93.4
93.5
N.A.
44.8
62.6
64.8
54.8
N.A.
45.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
66.6
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
93.3
13.3
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
64
0
64
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% E
% Phe:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
64
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
55
10
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
10
19
0
0
0
0
0
0
% K
% Leu:
0
64
73
64
0
0
19
0
10
0
0
10
0
64
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
64
0
0
0
10
0
0
10
0
0
% N
% Pro:
0
10
10
10
0
10
0
10
0
0
0
0
0
0
64
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
64
0
10
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
10
64
64
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
55
0
55
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _